Mutation Problems
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by Kathy Egbert
| 17 Questions
1
1
Transcribe the following DNA:TAC AAA TAT CGG TTT CCG CAA TCG ATA AGG GGG GCA This represents the normal mRNA.
2
1
Translate the mRNA in your answer above into a protein sequence. (spell each amino acid correctly and put a dash and no spaces between each).This represents the normal protein.
For Questions #3 - 7
Suppose the bases in the DNA above (TAC AAA TAT CGG TTT CCG CAA TCG ATA AGG GGG GCA) were not transcribed correctly and the mRNA now read:

AUG UUU AUA GCC AAG GGC GUU AGC UAU UCC CCC CGU
3
1
Compare this new mRNA to the normal mRNA in question #1. How many mistakes were made during transcription?
4
1
Translate the mRNA above into a protein sequence. (spell each amino acid correctly and put a dash and no spaces between each).
5
1
Were any amino acids changed due to any mistakes? If so, which ones?
6
1
What group of mutation is this?
gene mutation
chromosomal mutation
7
1
What type of mutation is this?
For Questions #8 - 12
Suppose the bases in the DNA above (TAC AAA TAT CGG TTT CCG CAA TCG ATA AGG GGG GCA) were not transcribed correctly and the mRNA now read:

AUG UUU AUA GCC AAA GGC GUA GCU AUU CCC CCC GU
8
1
Translate the mRNA above into a protein sequence. (spell each amino acid correctly and put a dash and no spaces between each).
9
1
How many amino acids changed due to any mistakes?
10
1
What group of mutation is this?
gene mutation
chromosomal mutation
11
1
What type of mutation is this?
12
1
Which of the two types of mutations had the greatest effect on the protein?
Mutations Diagram For Questions #13 - 17
13
1
What group of mutations do the diagrams above belong to?
14
1
What type of mutation is #1 in the diagram above?
15
1
What type of mutation is #2 in the diagram above?
16
1
What type of mutation is #3 in the diagram above?
17
1
What type of mutation is #4 in the diagram above?
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